Acute heart failure: does etiology matter?

نویسندگان

چکیده

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Patients (pts) with acute heart failure (AHF) are a heterogeneous population. The etiology the disfunction may play role in prognosis. Risk stratification at admission help predict in-hospital complications and needs. Objective To explore predictors mortality (IHM), post discharge early [1-month (1mM)] late [1-year (1yM)] readmission, respectively 1-month readmission (1mRA) 1-year (1yRA), our center population, using real-life data. Methods Based on single-center retrospective study, data collected from patients admitted Cardiology department AHF between 2010 2017. Pts without previous cardiovascular history or uncompleted clinical were excluded. pts divided 3 groups: ischemic (IE), valvular (VE) other etiologies (OE), which included hypertensive idiopathic cardiomyopathies). Statistical analysis used non-parametric tests Kaplan-Meyer survival analysis. Results We 300 AHF. Mean age was 67.4 ± 12.6 years old 72.7% male. 37.7% had revascularization procedures, 66.9% hypertension, 41% diabetic 38% dyslipidaemia. IE 45%, VE 22.7% OE 32.3% cases. There no significant differences groups regarding body mass index, Killip-Kimball class, systolic blood pressure admission, aspects (namely, creatinine, sodium urea), inotropes’ usage need non-invasive invasive ventilation. However, group higher percentage males comparing to e (83.0% vs 55.9% 70.1%, respectively, p < 0.001), rates prior procedures (68.9%, 19.1%, 7.2%, 0.001) traditional risk factors, namely hypertension (74.1% 57.7%, = 0.014), diabetes mellitus (48.1% 27.9% 27.8%, 0.002) dyslipidaemia (48.9% 30.9% 40.2%, 0.022). younger compared (63.9 13.5 68.9 11.1 69.5 13.0 old, 0.003). less left ventricle (left ejection fraction 40.8 14.1 32.2 9.8 31.6 12.8%, 0.001). showed IHM (IE 5.2% 8.8% 2.1%, 0.146), 1mRA 8.1&, 7.4%, 3.1%, 0.276) 1yRA 55.6%, 54.4%, 47.4%, 0.449). 1mM (VE 13.2% 8.9% 0.05) 1yM (33.8% 30.4% 17.5%, 0.34). These represented Kaplan Meier curves. Conclusion In predictor post-discharge but not readmission.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

[Heart failure: etiology and approach to diagnosis].

In spite of its high prevalence and the huge burden it imposes on health care systems, heart failure is a clinical syndrome that has not yet been defined satisfactorily. In actual practice, diagnosis requires the presence of typical signs and symptoms along with data from complementary tests that indicate definite cardiac dysfunction. In this article we review current concepts of the disease, s...

متن کامل

Acute heart failure facts and numbers: acute heart failure populations

Acute heart failure (AHF) is a life-threatening emergency, which largely profits from early diagnosis and treatment. The prevalence of AHF is difficult to assess, estimates range between 1 and 12% in the general population. Despite recent therapeutic advances, in-hospital mortality is high with estimates varying from 4 and 18% in different registries. Due to large differences in AHF definitions...

متن کامل

Increased endothelin levels in congestive heart failure: does it come from the lungs? Does it matter?

Endothelin-1 (ET) is a potent vasoconstrictor and promitogenic peptide produced ubiquitously by the vascular endothelium. It is formed by cleavage of the 39amino acid precursor big endothelin-1 (big ET) through the action of the endothelin converting enzymes (ECEs). Although it is generally accepted that ET is released constitutively in a preferentially paracrine fashion, a smaller, measurable ...

متن کامل

Heart failure prognosis: comorbidities matter.

BACKGROUND Prior risk prediction models have included a selective group of broad comorbidities in scoring prognosis of heart failure (HF) patients. OBJECTIVE We examined whether scoring a comprehensive set of comorbidities separately, could improve the performance and accuracy of predicting HF prognosis. METHODS This is a cross-validated, longitudinal, retrospective, observational study. Da...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: European Journal of Preventive Cardiology

سال: 2021

ISSN: ['2047-4881', '2047-4873']

DOI: https://doi.org/10.1093/eurjpc/zwab061.021